Yoshii F, Ooki N, Shinohara Y, Uehara K, Mochimaru F
Department of Neurology, Tokai University School of Medicine, Isehara, Japan.
Neurology. 1999 Jul 13;53(1):225-7. doi: 10.1212/wnl.53.1.225.
A 26-year-old woman on human menopausal gonadotrophin-human chorionic gonadotrophin therapy for sterility showed multiple cerebral infarctions associated with ovarian hyperstimulation syndrome. A hypercoagulable state (hemoconcentration, increased plasma levels of D-dimer and thrombin-antithrombin III complex, and decreased protein S activity) was associated with her thromboembolic events. Cerebral infarction associated with mild neurologic deficits may be overlooked in patients with ovarian hyperstimulation syndrome.
一名26岁因不育接受人绝经期促性腺激素-人绒毛膜促性腺激素治疗的女性出现了与卵巢过度刺激综合征相关的多发性脑梗死。高凝状态(血液浓缩、D-二聚体和凝血酶-抗凝血酶III复合物血浆水平升高以及蛋白S活性降低)与她的血栓栓塞事件相关。在卵巢过度刺激综合征患者中,伴有轻度神经功能缺损的脑梗死可能会被忽视。