The effect of (4-acetamido-phenyl)-2-acetoxy-benzoate (benorilate, Benortan) on the inflammatory process was studied thermographically and histologically in cotton-pellet tests on rats. 2. Following implantation of the cotton-pellet, thermography shows a clear inhibition of the local inflammation due to treatment with benorilate. 3. Histological examination shows a corresponding influence of benorilate upon the proliferative phase of the inflammation. 4. The success of antiphlogistic therapy is in correlation with the time of medication.