Rubin B P, Fletcher J A
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Adv Anat Pathol. 1999 Jul;6(4):204-12.
Skeletal myxoid chondrosarcoma is a histologic variant of conventional skeletal myxoid chondrosarcoma, whereas extraskeletal myxoid chondrosarcoma is a distinct entity characterized by a reciprocal t(9;22) translocation resulting in fusion of the EWS and CHN genes. Rarely, extraskeletal myxoid chondrosarcoma can occur in bone, and it is difficult to describe such tumors, unambiguously, using the present nomenclature. Designation as "chordoid sarcoma of bone" would distinguish these cases from conventional skeletal myxoid chondrosarcoma.
骨黏液样软骨肉瘤是传统骨黏液样软骨肉瘤的一种组织学变体，而骨外黏液样软骨肉瘤是一种独特的实体，其特征是存在导致EWS和CHN基因融合的t(9;22)相互易位。骨外黏液样软骨肉瘤很少发生于骨，使用目前的命名法很难明确描述这类肿瘤。将其命名为“骨脊索样肉瘤”可以将这些病例与传统骨黏液样软骨肉瘤区分开来。
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