Kantakamalakul W, Naksawat P, Kanyok R, Puthavathana P
Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 1999 Mar;82(3):263-7.
A total of 62 clinical specimens from the genital tract of patients who were suspected of contracting genital herpes were investigated for HSV infection by the virus isolation method, and also investigated for the co-infection with EBV infection by detecting EBV DNA using nested PCR. HSV infection was diagnosed in 30 (48.4%) of the study cases, and so was EBV. EBV DNA was present in 17 (56.7%) of the 30 HSV positive samples. No correlation was found between the co-existence of these two viruses together. EBV DNA was detected in genital specimens of cervical, vaginal, urethral, and anal swabs. Ninety per cent of EBV belonged to type 1, and the remainder belonged to type 2 and mixed types. The role of EBV in genital tract infection needs to be further investigated.
采用病毒分离法对62例疑似感染生殖器疱疹患者的生殖道临床标本进行单纯疱疹病毒（HSV）感染检测，并采用巢式聚合酶链反应（PCR）检测EB病毒（EBV）DNA，以研究是否存在EBV合并感染。研究病例中，30例（48.4%）诊断为HSV感染，EBV感染情况与之相同。30份HSV阳性样本中，17份（56.7%）检测到EBV DNA。未发现这两种病毒共存之间存在相关性。在宫颈、阴道、尿道和肛门拭子的生殖器标本中检测到EBV DNA。90%的EBV属于1型，其余为2型和混合型。EBV在生殖道感染中的作用有待进一步研究。
