Pita-Ramírez L, Cabrera Carbajal B E, Ortega Zavala C
Servicio de Hematología, Hospital General Vasco de Quiroga (HG-VQ), Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Morelia, Michoacán.
Rev Invest Clin. 1999 Mar-Apr;51(2):89-92.
To assess the fresh-frozen plasma (FFP) transfusion indications in a Mexican hospital.
A general hospital for federal government employees located in the city of Morelia, State of Michoacan, Mexico.
We evaluated all FFP transfusions between February and August, 1998 classifying them as appropriate or inappropriate according to the recent FFP-transfusion guidelines: correction of known coagulation factor deficiencies with bleeding and correction of microvascular bleeding when prothrombin and activated partial thromboplastin time are > 1.6 times normal (coagulation index o CI), urgent reversal of warfarin therapy, antithrombin III deficiency, thrombotic thrombocytopenic purpura treatment, liver transplant and acute disseminated intravascular coagulation.
78 patients with 292 FFP units transfused were analyzed: in 20 patients the indication was clotting support, 16 with CI < 1.5 and four with CI > 1.6, one with blood loss and one with surgical procedure; hypoalbuminemia in 10; hypovolemia in eight; unidentified reason in 33 and others in seven patients. Eleven units (3.76%) were considered properly transfused whereas 281 (96.23%) were inadequately indicated.
评估墨西哥一家医院新鲜冰冻血浆（FFP）的输血指征。
位于墨西哥米却肯州莫雷利亚市的一家联邦政府雇员综合医院。
我们评估了1998年2月至8月期间所有的FFP输血情况，并根据最近的FFP输血指南将其分类为适当或不适当：用于纠正已知凝血因子缺乏伴出血情况，以及当凝血酶原时间和活化部分凝血活酶时间>正常的1.6倍（凝血指数o CI）时纠正微血管出血，紧急逆转华法林治疗，抗凝血酶III缺乏，血栓性血小板减少性紫癜治疗，肝移植以及急性弥散性血管内凝血。
分析了78例输注292单位FFP的患者：20例患者的输血指征是凝血支持，其中16例CI < 1.5，4例CI > 1.6，1例因失血，1例因手术；10例存在低白蛋白血症；8例存在低血容量；33例原因不明，7例患者有其他情况。11单位（3.76%）被认为输血适当，而281单位（96.23%）输血指征不适当。
