Schliephake H, Schmelzeisen R, Neukam F W, Schierle H P, Scheller H
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Medizinische Hochschule Hannover.
Mund Kiefer Gesichtschir. 1999 May;3 Suppl 1:S106-9. doi: 10.1007/PL00014495.
A total of 409 implants was inserted into 83 consecutive patients, who had tumor-related intraoral resections of soft tissue and bone. A life table analysis was used to determine the survival rate of the implants placed over a period of 13 years. Log rank tests and a Cox regression analysis were employed to identify relevant effects of surgical parameters on implant survival. A total of 38 implant failures were encountered. Most of the losses (n = 16) occurred during the first year of functional loading. The cumulative, overall survival rate of implants was 56.5%. Previous radiation therapy, insertion into grafted bone or original jaw bone, and insertion into microsurgically revascularized grafts did not significantly affect the survival rates. In the Cox regression, only the timing of implant placement was significantly related to the survival rate in the group of patients with bone grafts (P = 0.0197), with a lower survival rate of 36.2% of primary inserted implants and 67.1% survival in the group with secondary implant placement.
总共为83例连续患者植入了409颗种植体，这些患者均进行了与肿瘤相关的口腔软组织和骨组织切除手术。采用寿命表分析法来确定在13年期间植入种植体的存活率。运用对数秩检验和Cox回归分析来确定手术参数对种植体存活的相关影响。总共出现了38例种植体失败。大多数失败情况（n = 16）发生在功能加载的第一年。种植体的累积总体存活率为56.5%。先前的放射治疗、植入移植骨或原颌骨以及植入显微外科血管化移植物对存活率没有显著影响。在Cox回归分析中，仅种植体植入时间与骨移植患者组的存活率显著相关（P = 0.0197），初次植入种植体的存活率较低，为36.2%，二次植入种植体组的存活率为67.1%。
