Watterson A E
Centre for Occupational and Environmental Health, De Montfort University, Leicester, UK.
Toxicol Lett. 1999 Jun 30;107(1-3):241-8. doi: 10.1016/s0378-4274(99)00053-3.
(1) To assess aspects of occupational and related environmental health risk assessment and risk management decisions of UK regulatory bodies on diazinon used in sheep dip; and (2) to benchmark those decisions against 'the public health precautionary approach'.
Analysis of diazinon health and safety data available within Government Departments, industry and from users in animal husbandry practice.
(1) Data on diazinon produced by the manufacturing companies for the UK pesticide regulatory agencies are not fully transparent; (2) UK regulatory health and safety processes assume accuracy of manufacturer's data and information provided on personal protective equipment (PPE) and application effectiveness; (3) data available reveal gaps and problems with diazinon toxicity, PPE and application methods; and (4) little published evidence shows that industry followed up the health of dippers after product registration or that government departments adopted a public health approach to regulation.
Diazinon sheep dip illustrates the need for the application of a rigorous precautionary principle in both initial registration and later monitoring of chemicals.
(1)评估英国监管机构对用于羊药浴的二嗪农的职业及相关环境卫生风险评估和风险管理决策的各个方面;(2)对照“公共卫生预防方法”对这些决策进行基准评估。
分析政府部门、行业以及畜牧业实际使用者中可获取的二嗪农健康与安全数据。
(1)制造公司为英国农药监管机构提供的二嗪农数据并不完全透明;(2)英国监管健康与安全流程假定制造商提供的数据以及关于个人防护装备(PPE)和施用效果的信息准确无误;(3)现有数据揭示了二嗪农毒性、PPE和施用方法方面的差距和问题;(4)鲜有公开证据表明行业在产品注册后对药浴者的健康进行跟踪,或政府部门采用公共卫生方法进行监管。
二嗪农羊药浴表明在化学品的初始注册和后续监测中都需要应用严格的预防原则。