• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人类GATA-3基因的胚胎表达。

Embryonic expression of the human GATA-3 gene.

作者信息

Debacker C, Catala M, Labastie M C

机构信息

Institut d'Embryologie Cellulaire et Moléculaire, CNRS UPR 9064, 49bis avenue de la Belle Gabrielle, 94736, Nogent-sur-Marne cedex, France.

出版信息

Mech Dev. 1999 Jul;85(1-2):183-7. doi: 10.1016/s0925-4773(99)00088-x.

DOI:10.1016/s0925-4773(99)00088-x
PMID:10415360
Abstract

The spatial and temporal analysis of GATA-3 expression pattern in the human embryo revealed its expression in new anatomical sites. These include the endoderm of the primitive foregut, pharynx and allantois, the branchial arches and the mesenchymal cells surrounding the stomach and dorsal aorta. On the other hand, human (h) GATA-3 expression in the central nervous system, somites and embryonic kidney confirms the tissue specificity of this gene throughout vertebrate evolution.

摘要

对人类胚胎中GATA-3表达模式的时空分析揭示了其在新解剖部位的表达。这些部位包括原始前肠、咽和尿囊的内胚层、鳃弓以及围绕胃和背主动脉的间充质细胞。另一方面,人类(h)GATA-3在中枢神经系统、体节和胚胎肾中的表达证实了该基因在整个脊椎动物进化过程中的组织特异性。

相似文献

1
Embryonic expression of the human GATA-3 gene.人类GATA-3基因的胚胎表达。
Mech Dev. 1999 Jul;85(1-2):183-7. doi: 10.1016/s0925-4773(99)00088-x.
2
Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements.启动子近端调控元件对小鼠GATA-3转录的时空控制
Dev Biol. 1997 Aug 1;188(1):1-16. doi: 10.1006/dbio.1997.8575.
3
Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system.转录因子GATA-2和GATA-3在小鼠中枢神经系统发育过程中的表达及基因相互作用
Dev Biol. 1999 Jun 15;210(2):305-21. doi: 10.1006/dbio.1999.9278.
4
Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis.GATA-3在淋巴细胞分化和小鼠胚胎发育过程中的表达。
Dev Immunol. 1992;3(1):1-11. doi: 10.1155/1992/27903.
5
The GATA-3 gene is expressed during human kidney embryogenesis.
Kidney Int. 1995 Jun;47(6):1597-603. doi: 10.1038/ki.1995.223.
6
GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development.GATA-5:一种在胚胎发育过程中以新的时空限制模式表达的转录激活因子。
Dev Biol. 1997 Mar 1;183(1):21-36. doi: 10.1006/dbio.1996.8485.
7
Lmo2 and GATA-3 associated expression in intraembryonic hemogenic sites.Lmo2和GATA-3在胚胎内造血位点的相关表达。
Development. 2000 Feb;127(3):643-53. doi: 10.1242/dev.127.3.643.
8
Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus.GATA-3基因座中泌尿生殖系统、中枢神经系统和心内膜特异性转录调控元件的定位。
Mol Cell Biol. 1999 Feb;19(2):1558-68. doi: 10.1128/MCB.19.2.1558.
9
Expression of GATA-binding proteins during embryonic development in Xenopus laevis.非洲爪蟾胚胎发育过程中GATA结合蛋白的表达
Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10642-6. doi: 10.1073/pnas.88.23.10642.
10
Regulation of GATA gene expression during vertebrate development.脊椎动物发育过程中GATA基因表达的调控。
Semin Cell Dev Biol. 2005 Feb;16(1):71-81. doi: 10.1016/j.semcdb.2004.10.002. Epub 2004 Dec 10.

引用本文的文献

1
Arrayed single-gene perturbations identify drivers of human anterior neural tube closure.阵列式单基因扰动确定人类前神经管闭合的驱动因素。
bioRxiv. 2025 Jul 22:2025.07.21.665862. doi: 10.1101/2025.07.21.665862.
2
Integrative Analysis of Expression and Variants as Prognostic Biomarkers in Urothelial Cancer.尿路上皮癌中作为预后生物标志物的表达与变异的综合分析
Int J Mol Sci. 2025 Jul 2;26(13):6378. doi: 10.3390/ijms26136378.
3
Is GATA3 Useful for Differentiating between Classical Hodgkin Lymphoma and Nodular Lymphocyte-Predominant Hodgkin lymphoma? A Two-Center Study in Tehran, Iran during 2016 to 2022.
GATA3对鉴别经典型霍奇金淋巴瘤和结节性淋巴细胞为主型霍奇金淋巴瘤是否有用?2016年至2022年在伊朗德黑兰进行的一项双中心研究。
Asian Pac J Cancer Prev. 2025 Apr 1;26(4):1421-1427. doi: 10.31557/APJCP.2025.26.4.1421.
4
GATA3 amplification is associated with high grade disease in non-invasive urothelial bladder cancer but unrelated to patient prognosis.GATA3基因扩增与非侵袭性膀胱尿路上皮癌的高级别病变相关,但与患者预后无关。
BMC Urol. 2025 Feb 20;25(1):37. doi: 10.1186/s12894-025-01704-y.
5
Identification and in vivo functional analysis of a novel missense mutation in GATA3 causing hypoparathyroidism, sensorineural deafness and renal dysplasia syndrome in a Chinese family.中国一个家系中导致甲状旁腺功能减退、感音神经性耳聋和肾发育不良综合征的GATA3基因新错义突变的鉴定及体内功能分析
Endocrine. 2025 Mar;87(3):1194-1203. doi: 10.1007/s12020-024-04087-6. Epub 2024 Nov 7.
6
Comparative Analysis of Transcription Factors TWIST2, GATA3, and HES5 in Glioblastoma Multiforme : Evaluating Biomarker Potential and Therapeutic Targets Using in Silico Methods.多形性胶质母细胞瘤中转录因子TWIST2、GATA3和HES5的比较分析:使用计算机方法评估生物标志物潜力和治疗靶点
J Korean Neurosurg Soc. 2025 Mar;68(2):202-212. doi: 10.3340/jkns.2024.0149. Epub 2024 Oct 24.
7
Transcriptional and epigenetic characterization of a new in vitro platform to model the formation of human pharyngeal endoderm.转录组学和表观遗传学表征人类咽内胚层形成的新型体外模型平台。
Genome Biol. 2024 Aug 8;25(1):211. doi: 10.1186/s13059-024-03354-z.
8
Shared features in ear and kidney development - implications for oto-renal syndromes.耳肾发育的共同特征——对耳肾综合征的启示。
Dis Model Mech. 2024 Feb 1;17(2). doi: 10.1242/dmm.050447. Epub 2024 Feb 14.
9
Diagnostic and Prognostic Roles of GATA3 Immunohistochemistry in Urothelial Carcinoma.GATA3 免疫组化在尿路上皮癌中的诊断和预后作用。
Medicina (Kaunas). 2023 Aug 11;59(8):1452. doi: 10.3390/medicina59081452.
10
Clinical and molecular characteristics of two Italian kindreds with hypoparathyroidism, deafness and renal dysplasia (HDR) syndrome.两个患有甲状旁腺功能减退、耳聋和肾发育不良(HDR)综合征的意大利家族的临床和分子特征。
J Endocrinol Invest. 2024 Feb;47(2):469-478. doi: 10.1007/s40618-023-02171-8. Epub 2023 Aug 10.