人类GATA-3基因的胚胎表达。
Embryonic expression of the human GATA-3 gene.
作者信息
Debacker C, Catala M, Labastie M C
机构信息
Institut d'Embryologie Cellulaire et Moléculaire, CNRS UPR 9064, 49bis avenue de la Belle Gabrielle, 94736, Nogent-sur-Marne cedex, France.
出版信息
Mech Dev. 1999 Jul;85(1-2):183-7. doi: 10.1016/s0925-4773(99)00088-x.
The spatial and temporal analysis of GATA-3 expression pattern in the human embryo revealed its expression in new anatomical sites. These include the endoderm of the primitive foregut, pharynx and allantois, the branchial arches and the mesenchymal cells surrounding the stomach and dorsal aorta. On the other hand, human (h) GATA-3 expression in the central nervous system, somites and embryonic kidney confirms the tissue specificity of this gene throughout vertebrate evolution.
对人类胚胎中GATA-3表达模式的时空分析揭示了其在新解剖部位的表达。这些部位包括原始前肠、咽和尿囊的内胚层、鳃弓以及围绕胃和背主动脉的间充质细胞。另一方面，人类（h）GATA-3在中枢神经系统、体节和胚胎肾中的表达证实了该基因在整个脊椎动物进化过程中的组织特异性。
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