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[高危女性的宫颈癌筛查:可行吗?里昂三个郊区的宫颈癌筛查项目结果]

[Cervical cancer screening for high risk women: is it possible? Results of a cervical cancer screening program in three suburban districts of Lyon].

作者信息

Mignotte H, Perol D, Fontanière B, Nachury L P, Blanc-Jouvand A, Fouillat V, Chauvin F, Lasset C

机构信息

Association pour le dépistage du cancer du col utérin, BP 107, 69672 Bron Cedex.

出版信息

Bull Cancer. 1999 Jun;86(6):573-9.

Abstract

Between november 1993 and october 1996, a cervical screening program was proposed for women 25-65-year-old who tend to have little or no medical supervision, in three suburban districts of Lyon. The data and results of the two last Pap-smears have been collected together with details of gynecological follow-up. Both general practitioners and gynaecologists were actively involved. A total of 3,792 women (12.3% of the target) were registered, with a larger proportion of women over 60 (17.7%). According to the "Consensus of Lille", only 403 women (34.4%) had adequate screening (over 50 y: 25.8%, 35-49 y: 39.4%, 25-35 y: 36.5%) and 2,489 women had inappropriate gynaecological follow-up: no smear for 185 women (4.9%) and inadequate schedule of follow-up visits for 476 others (12.5%). Missing data (date or results of Pap smear) were noted for 1,828 patients (48.2%). The screening procedure for women over 50 years was carried out mainly by general practitioner. Of 3,127 registered smears, 62 positive results were found (2.1%). Of these women, 9 were lost to follow-up and 4 did not have appropriate tests. Others results were: 27 negative further investigations, 9 CIN1, 7 CIN2, 3 CIN3, 1 in situ carcinoma and 2 invasive carcinoma. Despite low participation, this pilot study indicates that a procedure can be established to integrate high risk women in cervical cancer screening programme. Active participation of general practitioners is essential.

摘要

1993年11月至1996年10月期间,在里昂的三个郊区为25至65岁、几乎没有或完全没有医疗监管的女性开展了一项宫颈癌筛查项目。收集了最近两次巴氏涂片的数据和结果以及妇科随访的详细信息。全科医生和妇科医生都积极参与其中。共有3792名女性(占目标人群的12.3%)登记参加,60岁以上的女性占比更大(17.7%)。根据“里尔共识”,只有403名女性(34.4%)进行了充分筛查(50岁以上:25.8%,35至49岁:39.4%,25至35岁:36.5%),2489名女性的妇科随访不当:185名女性(4.9%)未进行涂片检查,另外476名女性(12.5%)的随访安排不充分。1828名患者(48.2%)存在数据缺失(巴氏涂片的日期或结果)。50岁以上女性的筛查程序主要由全科医生进行。在3127次登记的涂片中,发现62例阳性结果(2.1%)。在这些女性中,9例失访,4例未进行适当检查。其他结果为:27例进一步检查为阴性,9例CIN1,7例CIN2,3例CIN3,1例原位癌和2例浸润癌。尽管参与率较低,但这项试点研究表明,可以建立一种程序,将高危女性纳入宫颈癌筛查项目。全科医生的积极参与至关重要。

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