Devalckenaere A, Odaert M, Trieu-Cuot P, Simonet M
Equipe Mixte INSERM-Université E99-19 and JE2225, Département de Pathogénèse des Maladies Infectieuses et Parasitaires, Institut de Biologie de Lille, France.
FEMS Microbiol Lett. 1999 Jul 1;176(1):229-33. doi: 10.1111/j.1574-6968.1999.tb13666.x.
We characterized Yersinia enterocolitica and Yersinia pseudotuberculosis insertion sequences related to insertion sequence 1541, recently identified in Yersinia pestis. For each of the two species, two insertion sequence copies were cloned and sequenced. Genetic elements from Y. pseudotuberculosis were almost identical to insertion sequence 1541, whereas these from Y. enterocolitica were less related. Phylogenetic analysis of the putative transposases encoded by insertion sequences from the three pathogenic members of the genus Yersinia showed that they clustered with those encoded by Escherichia coli and Salmonella enterica elements belonging to the insertion sequence 200/insertion sequence 605 group. Insertion sequences originating from Y. pestis and Y. pseudotuberculosis constitute a monophyletic lineage distinct from that of Y. enterocolitica.
我们对与最近在鼠疫耶尔森菌中鉴定出的插入序列1541相关的小肠结肠炎耶尔森菌和假结核耶尔森菌插入序列进行了表征。对于这两个物种中的每一个，克隆并测序了两个插入序列拷贝。来自假结核耶尔森菌的遗传元件与插入序列1541几乎相同，而来自小肠结肠炎耶尔森菌的遗传元件相关性较小。对耶尔森菌属三个致病成员的插入序列编码的假定转座酶进行的系统发育分析表明，它们与属于插入序列200/插入序列605组的大肠杆菌和肠炎沙门氏菌元件编码的转座酶聚集在一起。源自鼠疫耶尔森菌和假结核耶尔森菌的插入序列构成了一个与小肠结肠炎耶尔森菌不同的单系谱系。
