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毛细管电泳电动流动的数值模型

Numerical Model of Electrokinetic Flow for Capillary Electrophoresis.

作者信息

Hu L, Harrison JD, Masliyah JH

机构信息

Department of Chemical and Materials Engineering, University of Alberta, Edmonton, T6G 2G6, Canada

出版信息

J Colloid Interface Sci. 1999 Jul 15;215(2):300-312. doi: 10.1006/jcis.1999.6250.

DOI:10.1006/jcis.1999.6250
PMID:10419665
Abstract

A numerical study is presented for the steady electrokinetic flow in intersecting channels in a T-shaped configuration. The electric potential and space charge density distribution along the capillary are obtained numerically by solving the nonlinear Poisson-Boltzmann equation for arbitrary electrokinetic radius and arbitrary surface potential. The velocity and pressure profiles are obtained by solving a modified Navier-Stokes equation using a primitive variable algorithm. A systematic study of flow in T-shaped intersecting channels showed that the hydrodynamic effect is an important factor that influences fluid leakage out of a channel where the electric potential is left floating. It was found that the flow in each channel can be controlled by applying a potential at each reservoir connected to the end of a channel. Copyright 1999 Academic Press.

摘要

本文给出了对T形结构交叉通道中稳态电动流动的数值研究。通过求解任意电动半径和任意表面电势下的非线性泊松-玻尔兹曼方程,数值得到沿毛细管的电势和空间电荷密度分布。利用原始变量算法求解修正的纳维-斯托克斯方程,得到速度和压力分布。对T形交叉通道内流动的系统研究表明,流体动力学效应是影响电势处于自由状态的通道中流体泄漏的一个重要因素。研究发现,通过在连接通道末端的每个储液器上施加电势,可以控制每个通道内的流动。版权所有1999年学术出版社。

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