Yamashita T, Murakawa Y, Hayami N, Inoue M, Fukui E, Kasaoka Y, Omata M
Department of Cardiovascular Medicine, Faculty of Medicine, University of Tokyo, Japan.
Jpn Heart J. 1999 Mar;40(2):227-32. doi: 10.1536/jhj.40.227.
To examine the circadian and infradian rhythms of paroxysmal atrial fibrillation, the time and date of 85 arrhythmic attacks occurring over a period of 4 years were analyzed in a patient with reliable symptoms. In the hourly analysis, a remarkable circadian rhythm similar to the reported population circadian rhythm was observed. On a day basis, the distribution of the intervals between 2 successive episodes showed a significant departure from the exponential distribution, indicating the arrhythmia was not a simple probabilistic phenomenon. Spectrum analysis revealed a prominent peak occurring at about 0.3 cycles/day, suggesting a possible circasemiseptan rhythm. Thus, in this patient, paroxysmal atrial fibrillation was not a random event when observed not only from an hour incremental perspective but also from a day incremental perspective, suggesting the circadian and infradian rhythms of this arrhythmia.
为研究阵发性心房颤动的昼夜节律和亚昼夜节律，对一名症状确切的患者在4年期间发生的85次心律失常发作的时间和日期进行了分析。在每小时分析中，观察到一种与报道的人群昼夜节律相似的显著昼夜节律。按天计算，连续两次发作之间的间隔分布显著偏离指数分布，表明该心律失常不是一个简单的概率现象。频谱分析显示在约0.3次/天处有一个突出的峰值，提示可能存在近半周节律。因此，在该患者中，不仅从每小时增量的角度，而且从每天增量的角度观察时，阵发性心房颤动都不是一个随机事件，提示该心律失常存在昼夜节律和亚昼夜节律。
