Gaa J, Wendl K, Tesdal I K, Meier-Willersen H J, Lehmann K J, Böhm C, Möckel R, Richter A, Trede M, Georgi M
Institut für Klinische Radiologie, Klinikum Mannheim gGmbH, Universitätsklinikum, Fakultät für Klinische Medizin Mannheim, Universität Heidelberg.
Rofo. 1999 Jun;170(6):528-33. doi: 10.1055/s-2007-1011087.
To evaluate the accuracy of a non-invasive "all-in-one" staging MR method in patients with pancreatic tumors.
46 patients were prospectively evaluated by a combined MR imaging protocol including breath-hold T1- and T2-weighted pulse sequence, MRCP using a breath-hold 2D-RARE sequence, and breath-hold gadolinium-enhanced dual-phase 3D-MR angiography.
All pancreatic tumors were detected by the combination of cross-sectional imaging and MRCP. In spite of the use of MRCP, definitive differentiation between pancreatic carcinoma and chronic pancreatitis was not possible in 3 (6.5%) out of 46 cases. High quality 3D-MR angiograms were obtained in 43 (93.5%) cases. In 6 (13%) patients 3D-MRA showed an aberrant right hepatic artery. The overall accuracy of MRI in assessing extrapancreatic tumor spread, lymph node metastases, liver metastases, and vascular involvement was 95.7%, 80.4%, 93.5%, and 89.1%, respectively.
Due to its high accuracy, the "all-in-one" MR protocol may become the most important modality after clinical examination and ultrasound in the diagnostic work-up for most patients with suspicion of pancreatic tumors.
评估一种用于胰腺肿瘤患者的非侵入性“一体化”分期磁共振成像（MR）方法的准确性。
对46例患者采用联合MR成像方案进行前瞻性评估，该方案包括屏气T1加权和T2加权脉冲序列、使用屏气二维快速自旋回波（2D-RARE）序列的磁共振胰胆管造影（MRCP）以及屏气钆增强双期三维MR血管造影。
通过横断面成像和MRCP的联合检查，所有胰腺肿瘤均被检测到。尽管使用了MRCP，但46例中有3例（6.5%）无法明确区分胰腺癌和慢性胰腺炎。43例（93.5%）获得了高质量的三维MR血管造影图像。6例（13%）患者的三维MR血管造影显示存在变异的右肝动脉。MRI评估胰腺外肿瘤扩散, 淋巴结转移, 肝转移和血管受累的总体准确率分别为95.7%, 80.4%, 93.5%和89.1%。
由于其高准确性，对于大多数疑似胰腺肿瘤的患者，在临床检查和超声之后，“一体化”MR方案可能成为诊断检查中最重要的检查方式。
