Larsson D, Lager I, Nilsson P M
Health Centre Degeberga, County Hospital, Kristianstad.
Scand J Public Health. 1999 Jun;27(2):101-5.
Diabetes mellitus is a chronic metabolic disease with wide implications for well-being and social life. The aim of this cross-sectional, observational study was to describe possible differences in clinical characteristics, socio-economic factors and quality of life between diabetes patients in poor and good/acceptable metabolic control, as defined by levels of glycated haemoglobin A1c. From a population-based register of diabetes patients at a clinical chemistry department, we selected 96 subjects in poor metabolic control (HbA1c > 10%), and 96 subjects in good/acceptable (HbA1c 6.5-7.5%) metabolic control, matched for sex, age and duration of diabetes. Each participant was sent a self-administered questionnaire regarding medical history, family situation and socio-economic background, as well as self-rated health based on a validated instrument (SF-36). The diabetes patients in poor metabolic control reported more retinopathy, vascular complications and nervous problems than did the patients in acceptable metabolic control. Furthermore, the group in poor metabolic control was also characterized by a lower educational level, a higher number of sick leave days or disability pension and a lower degree of physical activity. Both of the diabetic groups reported lower scorings for physical functioning, general health, vitality and mental health, than did a comparable non-diabetic group from another study. In summary, diabetic patients in poor metabolic control have a lower educational level and report more complications, nervous problems, sick leave days and disability pensions than patients in good/acceptable metabolic control. The lower degree of physical activity adds to the problems of the first group and should be the target for intervention to achieve better metabolic control.
糖尿病是一种慢性代谢性疾病,对健康和社会生活有着广泛影响。本横断面观察性研究的目的是描述根据糖化血红蛋白A1c水平定义的代谢控制差与良好/可接受的糖尿病患者在临床特征、社会经济因素和生活质量方面可能存在的差异。我们从临床化学科基于人群的糖尿病患者登记册中,选取了96名代谢控制差(糖化血红蛋白A1c>10%)的受试者和96名代谢控制良好/可接受(糖化血红蛋白A1c 6.5 - 7.5%)的受试者,两组在性别、年龄和糖尿病病程方面进行了匹配。向每位参与者发送了一份关于病史、家庭情况和社会经济背景的自填问卷,以及基于有效工具(SF - 36)的自评健康状况问卷。与代谢控制可接受的患者相比,代谢控制差的糖尿病患者报告有更多的视网膜病变、血管并发症和神经问题。此外,代谢控制差的组还具有教育水平较低、病假天数或残疾抚恤金较多以及身体活动程度较低的特点。与另一项研究中的可比非糖尿病组相比,两组糖尿病患者在身体功能、总体健康、活力和心理健康方面的得分均较低。总之,与代谢控制良好/可接受的患者相比,代谢控制差的糖尿病患者教育水平较低,报告有更多并发症、神经问题、病假天数和残疾抚恤金。身体活动程度较低加剧了第一组患者的问题,应作为干预目标以实现更好的代谢控制。