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威廉姆斯综合征的早期发育(5至48个月)。对14名儿童的研究。

Early development (5 to 48 months) in Williams syndrome. A study of 14 children.

作者信息

Plissart L, Fryns J P

机构信息

Centre for Human Genetics, University Hospital of Leuven, Belgium.

出版信息

Genet Couns. 1999;10(2):151-6.

Abstract

At what age do children with Williams syndrome (WS) achieve major developmental milestones? Is their early development harmonious or are some of the typical discrepancies described in older children already noticeable? To address these questions we analysed information gathered over a five year period on 14 children with WS. Each child was evaluated at least twice between the ages of 5 and 48 months, using the Bayley Scales of Infant Development and during more informal observation sessions. Parents and professionals were also interviewed. This analysis provided us with an outline for "developmental norms" for children with WS and allowed us to conclude that, even before the age of 4 years, children with WS display a typical profile in their abilities. Expressive language skills are less delayed in contrast to the important delay in language comprehension and fine motor skills.

摘要

患有威廉姆斯综合征(WS)的儿童在什么年龄达到主要的发育里程碑?他们的早期发育是协调的,还是在大龄儿童中描述的一些典型差异在此时就已经很明显了?为了解决这些问题,我们分析了在五年时间里收集到的14名患有WS儿童的信息。每个孩子在5至48个月之间至少接受了两次评估,使用贝利婴儿发展量表,并在更非正式的观察环节中进行评估。我们还采访了家长和专业人士。该分析为患有WS的儿童提供了一份“发育规范”大纲,并使我们得出结论,即便是在4岁之前,患有WS的儿童在能力方面也呈现出典型特征。与语言理解和精细运动技能的显著延迟相比,表达性语言技能的延迟较小。

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