Martin-du Pan R C, Vonlanthen M C, Dubuis J M
Rev Med Suisse Romande. 1999 Jun;119(6):475-9.
We report the case of an atopic patient aged 16 with a perannual asthma. He has been treated since the age of 4 with inhaled corticosteroïds. His growth was regular until he was 14 when beclomethasone was replaced by fluticasone (both administered by pressurized inhaler) due to adrenal suppression. Growth inhibiting effects of different inhaled corticosteroids are discussed focusing mainly on their effect on collagen synthesis.
我们报告了一例16岁的特应性患者,患有常年性哮喘。他从4岁起就开始使用吸入性皮质类固醇进行治疗。在14岁之前,他的生长发育正常,由于肾上腺抑制,当时将倍氯米松替换为氟替卡松(均通过压力定量吸入器给药)。本文主要讨论了不同吸入性皮质类固醇对胶原蛋白合成的影响,进而探讨其生长抑制作用。