Dopaminergic influence on cardiovascular responses to exercise stress in hypertensive subjects.
作者信息
Blanco M, Hurtado N, Jelambi I, Pérez G, Carrillo M, Gómez J, Bravo C, Gomez H, Collet H, Velasco M
机构信息
Clinical Pharmacology Unit, Vargas Medical School, Central University of Venezuela, Caracas.
出版信息
Am J Ther. 1997 Jan;4(1):31-3. doi: 10.1097/00045391-199701000-00007.
Ten hypertensive subjects were studied at the Vargas Medical School in Caracas, Venezuela. They were submitted to submaximal treadmill exercises according to Bruce's protocol under treatment with dopaminergic drugs (metoclopramide, bromocriptine). Before and during submaximal exercises, metoclopramide caused a hypotensive effect accompanied by an increased heart rate, which was blocked by the administration of bromocriptine. We conclude that a probable dopaminergic modulatory influence takes place during exercise.
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