Blanco M, Hurtado N, Jelambi I, Pérez G, Carrillo M, Gómez J, Bravo C, Gomez H, Collet H, Velasco M
Clinical Pharmacology Unit, Vargas Medical School, Central University of Venezuela, Caracas.
Am J Ther. 1997 Jan;4(1):31-3. doi: 10.1097/00045391-199701000-00007.
Ten hypertensive subjects were studied at the Vargas Medical School in Caracas, Venezuela. They were submitted to submaximal treadmill exercises according to Bruce's protocol under treatment with dopaminergic drugs (metoclopramide, bromocriptine). Before and during submaximal exercises, metoclopramide caused a hypotensive effect accompanied by an increased heart rate, which was blocked by the administration of bromocriptine. We conclude that a probable dopaminergic modulatory influence takes place during exercise.
在委内瑞拉加拉加斯的瓦尔加斯医学院对10名高血压患者进行了研究。他们在接受多巴胺能药物（甲氧氯普胺、溴隐亭）治疗的情况下，按照布鲁斯方案进行次极量跑步机运动。在次极量运动前和运动期间，甲氧氯普胺引起血压降低并伴有心率加快，而溴隐亭的给药可阻断这种情况。我们得出结论，运动期间可能存在多巴胺能调节影响。
