Stasenko A A, Mendel' N A
Lik Sprava. 1999 Jan-Feb(1):76-9.
A comparative evaluation was done of factors of the local and systemic immunity in 18 patients with diffuse pyoperitonitis. Morphological (neutrophiles from the abdominal cavity in patients with peritonitis retrieve NBT in a diffuse-dotted fashion whereas neutrophiles of blood give a diffuse pattern and by granules) and functional (reduced metabolic activity of abdominal neutrophiles in a spontaneous NBT-test and an augmented index for the reserve versus metabolic activity of blood neutrophiles) differences in local and systemic factors of immune defence were noted. It is shown that the content of all classes of immunoglobulins is significantly lower in the peritoneal exudate than it is in blood serum. The above facts are to be considered in treatment of patients with generalized purulent peritonitis.
对18例弥漫性脓性腹膜炎患者的局部和全身免疫因素进行了比较评估。发现免疫防御的局部和全身因素在形态学上(腹膜炎患者腹腔中的中性粒细胞以弥漫点状方式摄取NBT,而血液中的中性粒细胞则呈现弥漫模式并伴有颗粒)和功能上(在自发NBT试验中腹腔中性粒细胞代谢活性降低,而血液中性粒细胞储备与代谢活性指数增加)存在差异。结果表明,腹膜渗出液中所有类别的免疫球蛋白含量均显著低于血清。在治疗全身性化脓性腹膜炎患者时应考虑上述事实。