[The dynamics of the immune response and severity of the intoxication in peritonitis patients with open and closed management of the peritoneal cavity].

A comparative evaluation of clinico-immunological examinations of 45 patients with diffuse purulent peritonitis treated by the open method of management of the abdominal cavity and 46 patients treated by the traditional closed method was made. Pathogenetic grounds of the effectiveness of the open method of management of the abdominal cavity in patients with peritonitis are presented. Immunological alterations are shown allowing the evaluation of the severity of the state of patients in the postoperative period. They should be taken into account when prescribing the immunocorrective therapy.