Likhacheva E I, Semennikova T K, Vagina E R, Iarina A L, Klimina M S
Med Tr Prom Ekol. 1999(5):4-8.
The authors followed changes in clinical course of asbestosis, comparing groups of individuals working in exposure to chrysotile-asbestos dust, patients having so-called late asbestosis and reference group (individuals with absent or minimal roentgenologic changes in lungs). Analysis of 530 case histories proved increase of average length of service in dusty conditions before asbestosis development, longer progression of pulmonary fibrosis. Asbestosis progression does not depend on medical resolutions. "Late" asbestosis occurs in retired workers who were engaged into auxiliary occupations. Low baseline values of respiratory function and associated respiratory infection worsen the overall prognosis.
作者追踪了石棉沉着病临床病程的变化,比较了接触温石棉粉尘的工作人群、患有所谓晚期石棉沉着病的患者以及参照组(肺部X线变化缺失或轻微的个体)。对530份病历的分析证明,在石棉沉着病发展之前,接触粉尘环境下的平均工作年限增加,肺纤维化进展时间更长。石棉沉着病的进展不取决于医疗诊断。“晚期”石棉沉着病发生在从事辅助性职业的退休工人中。呼吸功能的低基线值及相关呼吸道感染会使总体预后恶化。