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[石棉沉着病患者结核病的临床和流行病学方面与粉尘负荷的关系]

[Clinical and epidemiologic aspects of tuberculosis in asbestosis patients in connection with dust load].

出版信息

Med Tr Prom Ekol. 2011(5):31-6.

Abstract

The article covers results of "case-control" study concerning clinical and epidemiologic aspects of tuberculosis in asbestosis patients, in connection with dust load. Findings are that the patients having asbestosis complicated with tuberculosis demonstrated total dust load (both in general dust weight and overall accumulated dose of respirable fibers of chrysotile asbestos) decreased with statistical significance, and therefore prevalence of tuberculosis among asbestosis patients decreased 5 times, in spite of growing prevalence of tuberculosis in Russia. Now the disease shows no progressive forms, light and medium course, lower prevalence of bacterioexcretion, longer survival of the patients. Trend of morbidity among the patients having asbestosis complicated with tuberculosis supports epidemiologic situation of tuberculosis in the country. Some workplaces remain with increased concentrations of chrysotile-containing dust, thus in future the patients having asbestosis complicated with tuberculosis could get occupational malignancies.

摘要

本文涵盖了一项“病例对照”研究的结果,该研究涉及石棉沉着病患者结核病的临床和流行病学方面,并与粉尘负荷相关。研究结果表明,患有石棉沉着病并伴有结核病的患者,其总粉尘负荷(包括一般粉尘重量和温石棉可吸入纤维的总累积剂量)有统计学意义的下降,因此,尽管俄罗斯结核病患病率呈上升趋势,但石棉沉着病患者中的结核病患病率却下降了5倍。目前,该病无进展型,病程为轻度和中度,细菌排泄率较低,患者生存期较长。石棉沉着病合并结核病患者的发病趋势与该国结核病的流行病学情况相符。一些工作场所含温石棉粉尘浓度仍然较高,因此,未来患有石棉沉着病并伴有结核病的患者可能会患上职业性恶性肿瘤。

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