下肢慢性静脉疾病：流行病学、结局、诊断与管理。静脉疾病特别行动小组循证报告摘要。静脉功能不全的流行病学和经济学研究。
Chronic venous disorders of the leg: epidemiology, outcomes, diagnosis and management. Summary of an evidence-based report of the VEINES task force. Venous Insufficiency Epidemiologic and Economic Studies.
作者信息
Kurz X, Kahn S R, Abenhaim L, Clement D, Norgren L, Baccaglini U, Berard A, Cooke J P, Cornu-Thenard A, Depairon M, Dormandy J A, Durand-Zaleski I, Fowkes G R, Lamping D L, Partsch H, Scurr J H, Zuccarelli F
机构信息
Department of Pharmacology, University of Liege, Belgium.
出版信息
Int Angiol. 1999 Jun;18(2):83-102.
BACKGROUND
To critically review the classification, epidemiology, outcomes, diagnosis and treatment of chronic venous disorders of the leg (CVDL), to issue evidence-based recommendations, and to identify areas requiring further research.
METHODS
Articles identified by an extensive literature search were scored by members of an international task force. Only those articles with a moderate or strong rating for internal validity were retained.
RESULTS
A scoring system weighing CVDL severity according to the probability of ulcer occurrence is proposed. Epidemiological data on the frequency of CVDL and its risk factors are reviewed. The following items are evaluated: costs associated with treatment; clinical outcomes related to CVDL and its treatment; available generic and disease-specific measures of quality of life; diagnostic procedures used to detect venous reflux; and efficacy of available treatments.
CONCLUSIONS
CVDL is an important public health problem, based on its prevalence, cost and impact on quality of life. High-priority areas for research on CVDL are identified.
背景
对下肢慢性静脉疾病（CVDL）的分类、流行病学、转归、诊断和治疗进行严格审查，发布基于证据的建议，并确定需要进一步研究的领域。
方法
通过广泛文献检索确定的文章由一个国际特别工作组的成员进行评分。仅保留那些内部效度评分为中等或高的文章。
结果
提出了一种根据溃疡发生概率衡量CVDL严重程度的评分系统。回顾了关于CVDL频率及其危险因素的流行病学数据。评估以下项目：治疗相关成本；与CVDL及其治疗相关的临床转归；现有的通用和特定疾病的生活质量测量方法；用于检测静脉反流的诊断程序；以及现有治疗方法的疗效。
结论
基于其患病率、成本和对生活质量的影响，CVDL是一个重要的公共卫生问题。确定了CVDL研究的高度优先领域。
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