Koudinova N V, Berezov T T, Koudinov A R
Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, 119832, Russia.
Biochemistry (Mosc). 1999 Jul;64(7):752-7.
This review considers some aspects of the biochemistry of beta-amyloid, a protein which produces insoluble deposits in the brain. These deposits are a specific morphological feature of Alzheimer's disease, Down's syndrome, and senile dementia. Our contribution to the concept of a soluble form of beta-amyloid as of a normal human protein is presented.
本综述探讨了β-淀粉样蛋白的生物化学某些方面，该蛋白在大脑中产生不溶性沉积物。这些沉积物是阿尔茨海默病、唐氏综合征和老年痴呆症的特定形态学特征。本文介绍了我们对于β-淀粉样蛋白可溶形式作为一种正常人类蛋白这一概念的贡献。
