β-淀粉样蛋白：阿尔茨海默病与脑β-淀粉样变性
Beta-amyloid: Alzheimer's disease and brain beta-amyloidoses.
作者信息
Koudinova N V, Berezov T T, Koudinov A R
机构信息
Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, 119832, Russia.
出版信息
Biochemistry (Mosc). 1999 Jul;64(7):752-7.
PMID:10424897
Abstract
This review considers some aspects of the biochemistry of beta-amyloid, a protein which produces insoluble deposits in the brain. These deposits are a specific morphological feature of Alzheimer's disease, Down's syndrome, and senile dementia. Our contribution to the concept of a soluble form of beta-amyloid as of a normal human protein is presented.
摘要
本综述探讨了β-淀粉样蛋白的生物化学某些方面，该蛋白在大脑中产生不溶性沉积物。这些沉积物是阿尔茨海默病、唐氏综合征和老年痴呆症的特定形态学特征。本文介绍了我们对于β-淀粉样蛋白可溶形式作为一种正常人类蛋白这一概念的贡献。
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