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恒河猴胎盘螺旋动脉及相关绒毛间隙的血流阻力

The flow resistance of the spiral artery and the related intervillous space in the rhesus monkey placenta.

作者信息

Moll W, Wallenburg H C, Kastendieck E, Voslar M

出版信息

Pflugers Arch. 1978 Nov 30;377(3):225-8. doi: 10.1007/BF00584276.

DOI:10.1007/BF00584276
PMID:104276
Abstract

Uteroplacental arteries of 4 rhesus monkeys were cannulated at their myometrical portions and perfused with dextran solutions and blood. Pressure-flow curves were obtained for the spiral artery and the related intervillous space, i.e. for the functional cotyledonary unit of the haemochorial villous placenta. For a flow of 3 ml.min-1, which is probably the normal rate of flow through the spiral artery, the pressure at the entry of the spiral artery was found to be 13--18 mm Hg (1.7--2.4kPa) during uterine relaxation (uterine diastole). There was a direct proportional relationship between the spiral artery flow and the pressure difference between the spiral artery and the amniotic fluid; the pressure difference per flow (the resistance of the cotyledonary unit) was found to be 1--3 mm Hg . ml-1 . min (8--24kPa . ml-1 . s). It is concluded that the spiral artery and the related intervillous space do not offer a limiting resistance to maternal blood flow in the absence of uterine contractions.

摘要

对4只恒河猴的子宫胎盘动脉在其子宫肌层部分进行插管,并灌注葡聚糖溶液和血液。获得了螺旋动脉及相关绒毛间隙的压力-流量曲线,即血绒毛膜胎盘功能叶单位的压力-流量曲线。对于3ml·min⁻¹的流量(这可能是通过螺旋动脉的正常流速),发现在子宫舒张期子宫松弛时,螺旋动脉入口处的压力为13 - 18mmHg(1.7 - 2.4kPa)。螺旋动脉血流量与螺旋动脉和羊水之间的压力差呈直接比例关系;每单位流量的压力差(叶单位的阻力)为1 - 3mmHg·ml⁻¹·min(8 - 24kPa·ml⁻¹·s)。得出的结论是,在没有子宫收缩的情况下,螺旋动脉及相关绒毛间隙对母体血流不构成限制性阻力。

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Hemoconcentration and pre-eclampsia.血液浓缩与子痫前期。

本文引用的文献

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DISTRIBUTION OF BLOOD FLOW IN ISOLATED LUNG; RELATION TO VASCULAR AND ALVEOLAR PRESSURES.离体肺脏的血流分布;与血管压力和肺泡压力的关系。
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[The uteroplacental circulation (author's transl)].[子宫胎盘循环(作者译)]
Z Geburtshilfe Perinatol. 1974 Feb;178(1):1-18.
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Sluice flow in placenta: maternal vascular pressure effects on fetal circulation.
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[Histological differences of placental villi within materno-fetal circulation units. Contribution to the functional morphology of the placenta].[母胎循环单元内胎盘绒毛的组织学差异。对胎盘功能形态学的贡献]
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