Tan H K, Smith J D, Goh D Y
Department of Otolaryngology, National University Hospital, Singapore, Singapore.
Int J Pediatr Otorhinolaryngol. 1999 Jun 15;49(1):53-61. doi: 10.1016/s0165-5876(98)00177-3.
Malformations of the tongue are rare. There are < 50 cases of tongue hypoplasia reported in the literature since the first case described by de Jussieu in 1718. These are usually associated with the hypoglossia-hypodactaly syndrome. We describe a newborn with a hypoplastic anterior tongue unfused to the posterior tongue and airway obstruction. Its embryology, theories of pathogenesis, treatment and clinical course are discussed.
舌部畸形较为罕见。自1718年德·朱西厄描述首例病例以来，文献中报道的舌发育不全病例不足50例。这些病例通常与舌下神经发育不全-指（趾）发育不全综合征相关。我们描述了一名患有前舌发育不全且与后舌未融合并伴有气道阻塞的新生儿。文中讨论了其胚胎学、发病机制理论、治疗方法及临床病程。
