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局部暴露于睾酮诱导两岁男孩性发育。

Sexual development in a two-year-old boy induced by topical exposure to testosterone.

作者信息

Yu Y M, Punyasavatsu N, Elder D, D'Ercole A J

机构信息

Division of Pediatric Endocrinology, Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina 27599-7220, USA.

出版信息

Pediatrics. 1999 Aug;104(2):e23. doi: 10.1542/peds.104.2.e23.

DOI:10.1542/peds.104.2.e23
PMID:10429141
Abstract

Virilization, including penile enlargement and growth of pubic hair and facial acne, developed in a 2-year-old boy over a period of months. This sexual development was induced by incidental and unintentional dermal exposure to a testosterone cream that was applied to his father's arm and back as a part of body building regimen. Except for penile size, the other signs of virilization diminished several months after the exposure was discontinued.

摘要

一名2岁男孩在数月内出现了男性化特征,包括阴茎增大、阴毛生长和面部痤疮。这种性发育是由于偶然且无意的皮肤接触了一种睾酮乳膏所致,该乳膏作为健身方案的一部分被涂抹在他父亲的手臂和背部。除阴茎大小外,在停止接触数月后,其他男性化体征有所减轻。

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Eur J Pediatr. 2005 Oct;164(10):646-7. doi: 10.1007/s00431-005-1714-z. Epub 2005 Jul 16.