Cheng L, Nascimento A G, Neumann R M, Nehra A, Cheville J C, Ramnani D M, Leibovich B C, Bostwick D G
Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis 46202, USA.
Cancer. 1999 Aug 1;86(3):498-504. doi: 10.1002/(sici)1097-0142(19990801)86:3<498::aid-cncr19>3.0.co;2-6.
Hemangioma of the urinary bladder is rare and the long term outcome of patients is unknown.
The authors evaluated the clinical and pathologic findings in 19 patients with a vesical hemangioma. All patients were treated at the Mayo Clinic between 1932-1998 and had histologic confirmation of the diagnosis. Hemangioma was classified into cavernous, capillary, or arteriovenous types based on conventional criteria from other sites. Clinical information was obtained from chart review. The mean follow-up of the patients was 6.9 years (range, 0.3-25 years).
The mean patient age at the time of diagnosis was 58 years (range, 19-76 years) and the male-to-female ratio was 3.7:1. Patients typically presented with macroscopic hematuria and endoscopic findings usually were nonspecific. The diagnosis of hemangioma was suspected in 3 patients (16%) prior to biopsy. There was a predilection for the posterior and lateral walls and the tumor usually was small (range, 0.2-3 cm; median, 0.7 cm) and solitary. The histologic types of hemangioma were cavernous (15 cases), capillary (2 cases), and arteriovenous (2 cases). All patients were treated with biopsy with or without fulguration, except for one patient who was treated with a partial cystectomy. No patients developed a recurrence during a mean follow-up of 6.9 years.
Patients with hemangioma of the urinary bladder have a favorable outcome. Biopsy and fulguration are effective for hemangioma of the bladder when the lesion is small.
膀胱血管瘤罕见，患者的长期预后尚不清楚。
作者评估了19例膀胱血管瘤患者的临床和病理表现。所有患者均于1932年至1998年在梅奥诊所接受治疗，且组织学确诊。根据其他部位的传统标准，血管瘤分为海绵状、毛细状或动静脉型。通过查阅病历获取临床信息。患者的平均随访时间为6.9年（范围0.3 - 25年）。
诊断时患者的平均年龄为58岁（范围19 - 76岁），男女比例为3.7:1。患者通常表现为肉眼血尿，内镜检查结果通常无特异性。3例患者（16%）在活检前被怀疑患有血管瘤。血管瘤好发于后壁和侧壁，肿瘤通常较小（范围0.2 - 3 cm；中位数0.7 cm）且为单发。血管瘤的组织学类型为海绵状（15例）、毛细状（2例）和动静脉型（2例）。除1例接受部分膀胱切除术的患者外，所有患者均接受了活检，部分患者还进行了电灼治疗。在平均6.9年的随访期间，无患者复发。
膀胱血管瘤患者预后良好。当病变较小时，活检和电灼治疗对膀胱血管瘤有效。
