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输尿管肉芽组织型血管瘤:一种极易误诊的疾病(附罕见病例报告并文献复习)。

Granulation tissue-type hemangioma of ureter: a highly misdiagnosed disease (a rare case report and literature review).

机构信息

Department of Urology, The First Hospital of Jilin University, Changchun, 130031, China.

Department of Urology, First Moscow State Medical University, Moscow, Russia, 119991.

出版信息

BMC Urol. 2022 Apr 19;22(1):63. doi: 10.1186/s12894-022-01010-x.

Abstract

BACKGROUND

Ureteral granulation tissue hemangiomas are rare benign vascular lesions, and they may be clinically asymptomatic or present with massive or recurrent hematuria. Sometimes hemangiomas are difficult to distinguish from malignant ureteral tumors, and most ureteral hemangiomas are confirmed by postoperative pathological examination. This article aims to present a case of granulation tissue-type hemangioma of the ureter and briefly review the current literature on this condition.

CASE PRESENTATION

A 30-year-old male patient presented with complaints of painless macroscopic hematuria for 2 months. Computerized tomography of the urinary system showed that the upper 1/3 of the right ureter was occupied, and then the possibility of tumor lesions was considered. The urine cytology showed occasional nuclear abnormalities and many light-stained crystals in urine. Because of suspicious radiological and cytological findings, the patient underwent the right ureteroscopy and the laparoscopic right ureteral mass resection. The postoperative pathological report showed that it was a mesenchymal tumor. The morphological and immunohistochemical staining was consistent with that of hemangioma, tending to granulation tissue hemangioma. After surgery, the patient was in a good state and recovered well at the last follow-up.

CONCLUSIONS

Ureteral granulation tissue hemangiomas are an easily misdiagnosed disease. Intermittent painless hematuria is an important characteristic of this disease. Therefore, we suggest that unnecessary radical surgery can be avoided when clinicians consider the possibility of benign ureteral tumors during the evaluation.

摘要

背景

输尿管肉芽组织血管瘤是罕见的良性血管病变,可能临床上无症状,或表现为大量或复发性血尿。有时血管瘤与恶性输尿管肿瘤难以区分,大多数输尿管血管瘤通过术后病理检查来确诊。本文旨在报告一例输尿管肉芽组织型血管瘤,并简要回顾该疾病的现有文献。

病例介绍

一名 30 岁男性患者因 2 个月无痛性肉眼血尿就诊。泌尿系统计算机断层扫描显示右输尿管上段 1/3 被占据,然后考虑肿瘤病变的可能性。尿液细胞学检查显示偶尔有核异常和尿液中有许多浅色结晶。由于影像学和细胞学检查可疑,患者接受了右输尿管镜检查和腹腔镜下右输尿管肿块切除术。术后病理报告显示为间叶性肿瘤。形态学和免疫组织化学染色与血管瘤一致,倾向于肉芽组织血管瘤。手术后,患者状态良好,最后一次随访时恢复良好。

结论

输尿管肉芽组织血管瘤是一种易误诊的疾病。间歇性无痛性血尿是该病的一个重要特征。因此,我们建议临床医生在评估良性输尿管肿瘤的可能性时,可以避免不必要的根治性手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091b/9017046/c8737425691d/12894_2022_1010_Fig1_HTML.jpg

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