17β-羟基类固醇脱氢酶（HSD）/17-酮类固醇还原酶（KSR）家族；17HSD/KSR酶的命名及主要特征
17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes.
作者信息
Peltoketo H, Luu-The V, Simard J, Adamski J
机构信息
Biocenter Oulu and WHO Collaborating Center for Research on Reproductive Health, University of Oulu, FIN-90220 Oulu, Finland.
出版信息
J Mol Endocrinol. 1999 Aug;23(1):1-11. doi: 10.1677/jme.0.0230001.
PMID:10431140
Abstract
A number of enzymes possessing 17beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase (17HSD/KSR) activities have been described and cloned, but their nomenclature needs specification. To clarify the present situation, descriptions of the eight cloned 17HSD/KSRs are given and guidelines for the classification of novel 17HSD/KSR enzymes are presented.
摘要
现已发现并克隆出多种具有17β-羟类固醇脱氢酶/17-酮类固醇还原酶（17HSD/KSR）活性的酶，但它们的命名需要规范。为阐明当前情况，本文给出了已克隆的8种17HSD/KSR的描述，并提出了新型17HSD/KSR酶的分类指南。
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