Rutala W A, Gergen M F, Weber D J
Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, 27599-7030, USA.
Infect Control Hosp Epidemiol. 1999 Jul;20(7):514-6. doi: 10.1086/501662.
This study was undertaken to evaluate the efficacy of a new low-temperature sterilization system that recently has been cleared by the Food and Drug Administration, the Sterrad 50. Flat stainless steel carriers were inoculated with approximately 10(6) Bacillus stearothermophilus spores. These carriers were placed aseptically in the middle of 40-cm-long stainless steel-lumened test units of varying diameters (1 mm, 2 mm, and 3 mm). After inoculation, the test units were processed in the Sterrad 50. After sterilization, the carriers were assayed for growth of the B. stearothermophilus spores. Our data demonstrated that the Sterrad 50 was highly effective in killing the B. stearothermophilus spores (no positive carriers with 30 tests of each lumen-diameter test unit). The Sterrad 50 is likely to be clinically useful for the sterilization of heat-sensitive medical equipment.
本研究旨在评估一种新的低温灭菌系统——Sterrad 50的有效性，该系统最近已获得美国食品药品监督管理局的批准。将扁平不锈钢载体接种约10(6)嗜热脂肪芽孢杆菌孢子。这些载体被无菌放置在不同直径（1毫米、2毫米和3毫米）、长40厘米的不锈钢内腔测试单元中间。接种后，测试单元在Sterrad 50中进行处理。灭菌后，检测载体上嗜热脂肪芽孢杆菌孢子的生长情况。我们的数据表明，Sterrad 50在杀灭嗜热脂肪芽孢杆菌孢子方面非常有效（每个内腔直径测试单元进行30次测试，无阳性载体）。Sterrad 50在临床上可能对热敏医疗设备的灭菌有用。
