Schlienger N, Peyrottes S, Aubertin A M, Gosselin G, Imbach J L, Périgaud C
Laboratoire de Chimie Bioorganique, U.M.R. CNRS 5625, Université Montpellier II, France.
Nucleosides Nucleotides. 1999 Apr-May;18(4-5):1025-6. doi: 10.1080/15257779908041638.
The synthesis and anti-HIV activities of phenyl S-pivaloyl-2-thioethyl (tBuSATE) phosphotriesters of AZT and d4T are reported. These compounds show similar activity compared to bis(tBuSATE) phosphotriesters and appear to be able to deliver the corresponding 5'-mononucleotides inside the cells.
报道了齐多夫定（AZT）和司他夫定（d4T）的苯基S-新戊酰基-2-硫代乙基（tBuSATE）磷酸三酯的合成及其抗HIV活性。与双（tBuSATE）磷酸三酯相比，这些化合物表现出相似的活性，并且似乎能够将相应的5'-单核苷酸递送至细胞内。
Zotero 插件