Caflisch C, Wang J, Zbinden R
Psychiatric University Clinic, Zurich, Switzerland.
Am J Public Health. 1999 Aug;89(8):1252-4. doi: 10.2105/ajph.89.8.1252.
Three filters were tested for in situ efficacy in reducing bacterial contamination associated with injection drug use.
In a self-matched control design with blinded laboratory testing, injection drug users were asked to use 3 filters in random succession when loading their syringes with drug solute.
The 0.22-micron filter proved significantly better than both the cigarette filter (relative risk [RR] = 18.0) and the 20-micron filter (RR = 4.5) in rendering syringes bacteria-free.
The 15- to 20-micron syringe filter currently provided injection drug users in Switzerland does not significantly reduce contamination associated with common bacterial infections among users. Filters with pore width 1/100th as large are recommended.
测试三种过滤器在减少与注射吸毒相关的细菌污染方面的原位功效。
在一项采用盲法实验室检测的自身匹配对照设计中,要求注射吸毒者在向注射器中装入药物溶质时依次随机使用三种过滤器。
在使注射器无菌方面,0.22微米过滤器被证明明显优于香烟过滤器(相对风险[RR]=18.0)和20微米过滤器(RR=4.5)。
瑞士目前为注射吸毒者提供的15至20微米注射器过滤器并不能显著减少使用者中常见细菌感染相关的污染。建议使用孔径为其1/100的过滤器。