Gomord V, Wee E, Faye L
Laboratoire des Transports Intracellulaires, CNRS-ESA 6037, IFRMP 23, Université de Rouen, Mont-Saint-Aignan, France.
Biochimie. 1999 Jun;81(6):607-18. doi: 10.1016/s0300-9084(99)80118-7.
Protein transport along the secretory pathway is supported by a noria of vesicles that bud and fuse, load and unload their cargo from one compartment into the other. However, despite this constant flow-through of proteins and lipids the various compartments of the secretory pathway are able to maintain their own specific composition. Here, we discuss recent insights into mechanisms of protein retention and localization that are necessary for the maintenance of endoplasmic reticulum (ER)- and Golgi-associated typical functions such as protein folding and glycosylation in plant cells.
沿着分泌途径的蛋白质运输由一群不断出芽和融合的囊泡所支持，这些囊泡将货物从一个区室装载和卸载到另一个区室。然而，尽管蛋白质和脂质不断地流经，分泌途径的各个区室仍能够维持其自身特定的组成。在这里，我们讨论了有关蛋白质保留和定位机制的最新见解，这些机制对于维持内质网（ER）和高尔基体相关的典型功能（如植物细胞中的蛋白质折叠和糖基化）是必需的。
