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香港患者的优化腹膜透析

Optimal peritoneal dialysis for patients from Hong Kong.

作者信息

Lai K N, Lo W K

机构信息

Department of Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam.

出版信息

Perit Dial Int. 1999;19 Suppl 3:S26-31; discussion S32-4.

PMID:10433549
Abstract

The socioeconomic statuses of Asian countries are diverse and government reimbursement policies for renal replacement programs vary greatly from one country to another. Both factors affect not only the availability of treatment but also the choice of dialysis modality. Despite the economic growth of Hong Kong over the past three decades, the resources spent by our government on health services are less than other developed countries. The National Health Service, which is run on a tight budget, supports almost 95% of the patients on renal replacement programs. Due to the cost-effectiveness and reimbursement from the government, 79% of patients with end-stage renal failure in Hong Kong are treated with continuous ambulatory peritoneal dialysis (CAPD). All new patients entering the renal replacement program run by the National Health Service are offered CAPD as the first-line dialytic treatment. Due to budgetary constraint, over the past 10 years dialysis centers in Hong Kong have adopted a small-volume regime of 3 x 2-L daily exchanges as the initial dialysis prescription. This dialysis prescription will be considered to be suboptimal by Western standards, but the survival of these patients was comparable to, or even better than, other areas despite a lower Kt/V. These preliminary studies suggest small-volume dialysis may be an acceptable compromise in Asian populations with their smaller body size, given the financial constraints. These issues are especially important in Asia, where financial resources for renal replacement therapy are still limited in most countries and many patients have to continue working to pay for their renal replacement treatment. Using this small-volume dialytic regime, more patients may be treated with the limited financial resources. Furthermore, our experience raises the question of the importance of nutritional status in patient survival.

摘要

亚洲国家的社会经济状况各不相同,各国政府对肾脏替代治疗项目的报销政策也存在很大差异。这两个因素不仅影响治疗的可及性,还影响透析方式的选择。尽管香港在过去三十年中经济有所增长,但政府在医疗服务上的支出仍低于其他发达国家。预算紧张的国民保健服务体系为近95%接受肾脏替代治疗项目的患者提供支持。由于成本效益和政府报销,香港79%的终末期肾衰竭患者接受持续性非卧床腹膜透析(CAPD)治疗。所有进入国民保健服务体系肾脏替代治疗项目的新患者都被提供CAPD作为一线透析治疗。由于预算限制,在过去十年中,香港的透析中心采用了每日3次、每次2升的小剂量透析方案作为初始透析处方。按照西方标准,这种透析处方可能被认为不够理想,但尽管Kt/V较低,这些患者的生存率与其他地区相当,甚至更高。这些初步研究表明,鉴于经济限制,对于体型较小的亚洲人群,小剂量透析可能是一种可接受的折衷方案。这些问题在亚洲尤为重要,因为在大多数国家,肾脏替代治疗的财政资源仍然有限,许多患者不得不继续工作以支付肾脏替代治疗费用。采用这种小剂量透析方案,可以用有限的财政资源治疗更多患者。此外,我们的经验提出了营养状况对患者生存重要性的问题。

相似文献

1
Optimal peritoneal dialysis for patients from Hong Kong.香港患者的优化腹膜透析
Perit Dial Int. 1999;19 Suppl 3:S26-31; discussion S32-4.
2
Current status of peritoneal dialysis in Korea: efforts to achieve optimal outcome.韩国腹膜透析的现状:为实现最佳治疗效果所做的努力。
Perit Dial Int. 1999;19 Suppl 3:S17-25.
3
Peritoneal dialysis in Asia.亚洲的腹膜透析
Perit Dial Int. 1996;16 Suppl 1:S381-5.
4
Relationship between adequacy of dialysis and nutritional status, and their impact on patient survival on CAPD in Hong Kong.香港持续性不卧床腹膜透析患者的透析充分性与营养状况的关系及其对患者生存的影响。
Perit Dial Int. 2001 Sep-Oct;21(5):441-7.
5
Development of the "peritoneal dialysis first" model in Hong Kong.香港“腹膜透析优先”模式的发展
Perit Dial Int. 2007 Jun;27 Suppl 2:S53-5.
6
ASPD: A prospective study of adequacy in Asian patients on long term, small volume, continuous ambulatory peritoneal dialysis.亚洲患者长期小容量持续性非卧床腹膜透析充分性的前瞻性研究
Perit Dial Int. 2006 Jul-Aug;26(4):466-74.
7
Dialysis adequacy of Asian patients receiving small volume continuous ambulatory peritoneal dialysis.接受小容量持续非卧床腹膜透析的亚洲患者的透析充分性
Int J Artif Organs. 1997 Aug;20(8):428-35.
8
Adequacy targets of peritoneal dialysis in the Asian population.亚洲人群腹膜透析的充分性目标
Perit Dial Int. 2001;21 Suppl 3:S378-83.
9
Automated peritoneal dialysis in Asia.亚洲的自动化腹膜透析
Perit Dial Int. 1999;19 Suppl 2:S125-9.
10
Continuous ambulatory peritoneal dialysis is better than automated peritoneal dialysis as first-line treatment in renal replacement therapy.在肾脏替代治疗中,持续非卧床腹膜透析作为一线治疗方法优于自动化腹膜透析。
Perit Dial Int. 2007 Jun;27 Suppl 2:S153-7.

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Long-term efficacy of intermittent peritoneal dialysis using various doses.不同剂量间歇性腹膜透析的长期疗效
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A study of the clinical and biochemical profile of peritoneal dialysis fluid low in glucose degradation products.一项关于葡萄糖降解产物低的腹膜透析液的临床和生化特征的研究。
Perit Dial Int. 2012 May-Jun;32(3):280-91. doi: 10.3747/pdi.2010.00176. Epub 2011 Nov 3.