Karabatsas C H, Cook S D, Sparrow J M
Department of Ophthalmology, Bristol Eye Hospital.
Br J Ophthalmol. 1999 Apr;83(4):403-9. doi: 10.1136/bjo.83.4.403.
To create a clinically useful classification for post-keratoplasty corneas based on corneal topography.
A total of 360 topographic maps obtained with the TMS-1, from 95 eyes that had undergone penetrating keratoplasty (PKP), were reviewed independently by two examiners in a masked fashion, and were categorised according to a proposed classification scheme.
A high interobserver agreement (88% in the first categorisation) was achieved. At 12 months post-PKP, a regular astigmatic pattern was observed in 20/85 cases (24%). This was subclassified as oval in three cases (4%), oblate symmetric bow tie in six cases (7%), prolate asymmetric bow tie in six cases (7%), and oblate asymmetric bow tie in five cases (6%). An irregular astigmatic pattern was observed in 61/85 cases (72%), subclassified as prolate irregular in five cases (6%), oblate irregular in four cases (5%), mixed in seven cases (8%), steep/flat in 11 cases (13%), localised steepness in 16 cases (19%), and triple pattern in three cases (4%). Regular astigmatic patterns were associated with significantly higher astigmatism measurements. The surface asymmetry index was significantly lower in the regular astigmatic patterns.
In post-PKP corneas, the prevalence of irregular astigmatism is about double that of regular astigmatism, with a trend for increase of the irregular patterns over time.
基于角膜地形图创建一种对角膜移植术后角膜具有临床实用性的分类方法。
两名检查者以盲法独立回顾了用TMS-1获得的95只接受穿透性角膜移植术(PKP)眼睛的360张地形图,并根据一种提议的分类方案进行分类。
观察者间一致性较高(首次分类时为88%)。在PKP术后12个月,20/85例(24%)观察到规则散光模式。其中3例(4%)为椭圆形,6例(7%)为扁圆形对称领结形,6例(7%)为长圆形不对称领结形,5例(6%)为扁圆形不对称领结形。61/85例(72%)观察到不规则散光模式,细分为5例(6%)长圆形不规则,4例(5%)扁圆形不规则,7例(8%)混合型,11例(13%)陡峭/扁平型,16例(19%)局部陡峭型,3例(4%)三重模式。规则散光模式与显著更高的散光测量值相关。规则散光模式的表面不对称指数显著更低。
在PKP术后角膜中,不规则散光的患病率约为规则散光的两倍,且不规则模式有随时间增加的趋势。