Somervaille T C, Kirk S, Dogan A, Landon G V, Mackinnon S
Department of Haematology, University College Hospital, London, UK.
Bone Marrow Transplant. 1999 Jul;24(1):99-101. doi: 10.1038/sj.bmt.1701854.
Adenoviruses are increasingly realised to be responsible for serious morbidity and mortality following allogeneic bone marrow transplantation. We describe a case of fulminant hepatic failure due to adenovirus serotype 2 in a 39-year-old woman who received a matched sibling allogeneic bone marrow transplant for multiply relapsed Hodgkin's disease. Isolated fulminant hepatic failure caused by this serotype of adenovirus has not previously been described.
人们越来越认识到腺病毒是异基因骨髓移植后导致严重发病和死亡的原因。我们描述了一例39岁女性因2型腺病毒导致暴发性肝衰竭的病例,该女性因多次复发的霍奇金淋巴瘤接受了同胞全相合异基因骨髓移植。此前尚未有过由这种血清型腺病毒引起的孤立性暴发性肝衰竭的报道。