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性传播疾病诊断检测的正确样本:哪种检测用哪种样本?

Correct samples for diagnostic tests in sexually transmitted diseases: which sample for which test?

作者信息

Stary A

机构信息

Outpatient's Center for Infectious Venero-dermatological Diseases and Fungal Infections, Vienna, Austria.

出版信息

FEMS Immunol Med Microbiol. 1999 Jul 15;24(4):455-9. doi: 10.1111/j.1574-695X.1999.tb01318.x.

DOI:10.1111/j.1574-695X.1999.tb01318.x
PMID:10435765
Abstract

Amplified DNA technology such as the polymerase chain reaction (PCR) and ligase chain reaction (LCR) are new techniques for the diagnosis of genital chlamydial infections in both men and women. These tests are highly sensitive and specific in detecting chlamydial genes in different specimen types such as genital samples as well as in non-invasive specimens such as urine and vulval smears. Due to the advantage of a high reliability of these techniques even when they are performed on non-invasive specimen types, amplification tests allow chlamydial diagnosis for screening especially high risk persons as the basis of chlamydia control programs.

摘要

诸如聚合酶链反应(PCR)和连接酶链反应(LCR)等扩增DNA技术是诊断男性和女性生殖道衣原体感染的新技术。这些检测在检测不同标本类型(如生殖道样本)以及非侵入性标本(如尿液和外阴涂片)中的衣原体基因时具有高度敏感性和特异性。由于这些技术即使在对非侵入性标本类型进行检测时也具有高可靠性的优势,扩增检测可用于衣原体诊断筛查,尤其是对高危人群进行筛查,作为衣原体控制项目的基础。

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引用本文的文献

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The laboratory diagnosis of Neisseria gonorrhoeae.淋病奈瑟菌的实验室诊断。
Can J Infect Dis Med Microbiol. 2005 Jan;16(1):15-25. doi: 10.1155/2005/323082.
2
Chlamydia trachomatis infections in Greece: first prevalence study using nucleic acid amplification tests.希腊沙眼衣原体感染情况:首次使用核酸扩增检测的患病率研究。
Eur J Clin Microbiol Infect Dis. 2005 Mar;24(3):207-13. doi: 10.1007/s10096-005-1296-8.