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[Acetaminophen hepatotoxicity in an alcohol addicted student. Case report].

作者信息

Fercovic A, Serra I, Serra L

机构信息

Hospital de Quellón, Santiago, Chile.

出版信息

Rev Med Chil. 1999 Feb;127(2):202-5.

Abstract

We report a 12 years old male with a history of excessive alcohol intake, that developed a severe liver failure after the use of acetaminophen in therapeutic doses. He presented with encephalopathy, jaundice, fever and an upper gastrointestinal bleeding. Serum aspartate aminotransferase values were 5,250 IU/L. The patient received supportive care and oral corticosteroids, remained severely compromised for 72 hours and had a good evolution thereafter. The association of acetaminophen use and excessive alcohol intake in a patient who developed an acute hepatic failure and the absence of serological evidence of hepatitis A or B viral infection, support the diagnosis of drug induced liver failure.

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