Kono T, Hayami M, Kobayashi H, Ishii M, Taniguchi S
Lancet. 1999 Jul 31;354(9176):396-7. doi: 10.1016/S0140-6736(99)02135-2.
A 58-year-old man with diabetes mellitus was treated with acarbose 300 mg daily. 13 days after the start of treatment with acarbose, generalised erythema multiforme developed with blood eosinophilia. Tissue eosinophilia was also found histologically. A challenge test for acarbose confirmed allergic reaction clinically and histologically.
一名58岁的糖尿病男性患者每天服用300毫克阿卡波糖进行治疗。在开始使用阿卡波糖治疗13天后，出现了泛发性多形红斑并伴有血液嗜酸性粒细胞增多。组织学检查也发现了组织嗜酸性粒细胞增多。阿卡波糖激发试验在临床和组织学上均证实了过敏反应。
