Department of Dermatology and Allergic Diseases, Universitätsklinikum Ulm, Life Science Building N27, James-Franck Ring/Meyerhofstrasse 11c, 89081, Ulm, Germany.
Department of Dermatology, Venereology, Allergology and Immunology, Städtisches Klinikum Dessau, Dessau, Germany.
Rev Endocr Metab Disord. 2016 Sep;17(3):269-282. doi: 10.1007/s11154-016-9373-0.
Diabetes is a debilitating, life-threatening disease accounting in 2015 for the death of 5 million people worldwide. According to new estimations, 415 million adults currently suffer from the disease, and this number is expected to rise to 642 million by 2040. High glucose blood levels also affect the skin among systemic organs, and skin disorders can often predict the onset of this metabolic disorder. In this review, we address the pathomechanistic effects of diabetes on the skin and give an overview on the most common skin diseases associated with diabetes.
糖尿病是一种使人虚弱、危及生命的疾病，2015 年全球有 500 万人因此死亡。根据新的估计，目前全球有 4.15 亿成年人患有这种疾病，到 2040 年，这一数字预计将上升至 6.42 亿。高血糖水平还会影响全身器官的皮肤，皮肤疾病往往可以预测这种代谢紊乱的发病。在这篇综述中，我们探讨了糖尿病对皮肤的病理机制影响，并概述了与糖尿病相关的最常见皮肤疾病。
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