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HIV相关神经心理损害与语义启动和重复启动的差异关联。

Differential association of HIV-related neuropsychological impairment with semantic versus repetition priming.

作者信息

Jasiukaitis P, Fein G

机构信息

Department of Psychiatry, University of California San Francisco, USA.

出版信息

J Int Neuropsychol Soc. 1999 Jul;5(5):434-41. doi: 10.1017/s1355617799555057.

DOI:10.1017/s1355617799555057
PMID:10439588
Abstract

There is evidence that the facilitating effects of stimulus repetition (repetition or identity priming) are mediated by visuoperceptual functions local to extrastriate cortex. Semantic or verbal-associative priming, on the other hand, is believed to be a function of more anterior brain systems. The present study finds evidence for disrupted semantic priming with intact repetition priming in a cognitively impaired HIV+ sample. These results are consistent with recent brain-imaging evidence for a subcortical and white-matter locus for HIV associated neuropathology resulting in effects on subcortical-frontal systems.

摘要

有证据表明,刺激重复(重复或同一性启动)的促进作用是由纹外皮层局部的视觉感知功能介导的。另一方面,语义或言语联想启动被认为是更靠前的脑系统的功能。本研究发现,在认知受损的HIV阳性样本中,存在重复启动完好但语义启动受损的证据。这些结果与最近的脑成像证据一致,即HIV相关神经病理学的皮层下和白质位点对皮层下-额叶系统产生影响。

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