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使用单词发音任务对思维紊乱的精神分裂症患者进行增强语义启动研究。

Enhanced semantic priming in thought-disordered schizophrenic patients using a word pronunciation task.

作者信息

Moritz S, Mersmann K, Kloss M, Jacobsen D, Andresen B, Krausz M, Pawlik K, Naber D

机构信息

Universitäts-Krankenhaus Hamburg-Eppendorf, Klinik für Psychiatrie und Psychotherapie, Martinistrasse 52, D-20246 Hamburg, Germany.

出版信息

Schizophr Res. 2001 Mar 30;48(2-3):301-5. doi: 10.1016/s0920-9964(00)00057-8.

DOI:10.1016/s0920-9964(00)00057-8
PMID:11295382
Abstract

Previous research on semantic priming in schizophrenia has produced contradictory findings. For the present study, it was intended to resolve some of the ambiguities in the literature. Using a semantic priming task with word pronunciation, evidence is provided that thought-disordered schizophrenic (TD) patients exhibit significantly increased semantic priming as compared to healthy and psychiatric controls. Results suggest that enhanced semantic priming is not confined to tasks that require lexical decision. Moreover, results indicate that TD schizophrenic patients suffer from a decay of hierarchical thinking, i.e. TD schizophrenics reveal a tendency to process the less meaningful rather than the dominant aspects of external information. Priming effects for the inferior meaning of homograph words (for example, 'dance' is an inferior, and 'game' is a superior associate of the word 'ball') were significantly greater compared to healthy controls and non-TD schizophrenics. Results were not moderated by sociodemographic background variables, psychomotor slowing and psychopathological symptoms other than thought disorder.

摘要

先前关于精神分裂症语义启动效应的研究得出了相互矛盾的结果。在本研究中,旨在解决文献中的一些模糊之处。通过使用一个涉及单词发音的语义启动任务,有证据表明,与健康对照组和精神科对照组相比,思维紊乱的精神分裂症(TD)患者表现出显著增强的语义启动效应。结果表明,增强的语义启动效应并不局限于需要词汇判断的任务。此外,结果表明,TD精神分裂症患者存在层次思维衰退,即TD精神分裂症患者表现出处理外部信息中意义较小而非主导方面的倾向。与健康对照组和非TD精神分裂症患者相比,同形异义词的次要意义的启动效应(例如,“舞蹈”是“球”这个词的次要关联,“游戏”是其主要关联)显著更大。结果不受社会人口统计学背景变量、精神运动迟缓以及除思维紊乱外的精神病理症状的影响。

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