Worm K, Dragsholt C, Simonsen K W, Kringsholm B
Retskemisk afdeling, Københavns Universitet.
Ugeskr Laeger. 1999 Jul 26;161(30):4291-2.
Citalopram was found in 92 autopsy cases and 27 cases from living persons and the concentrations are described. A range of 6.2-19 mumol/kg whole blood was found in cases where citalopram alone was the cause of death and a range of 1.9-16 mumol/kg whole blood in cases, where citalopram together with other compounds were considered to be the cause of death. In autopsy cases toxic concentrations were in the range 1.2-2.8 mumol/kg whole blood and concentrations between 0:09 and 1.9 mumol/kg were considered therapeutic. In cases from living persons the citalopram concentrations in whole blood were 0.06-0.9 mumol/kg.
在92例尸检病例和27例活体病例中发现了西酞普兰，并描述了其浓度。在仅以西酞普兰为死因的病例中，全血浓度范围为6.2 - 19 μmol/kg；在西酞普兰与其他化合物共同被认为是死因的病例中，全血浓度范围为1.9 - 16 μmol/kg。在尸检病例中，中毒浓度范围为1.2 - 2.8 μmol/kg全血，0.09至1.9 μmol/kg之间的浓度被认为是治疗浓度。在活体病例中，全血中西酞普兰浓度为0.06 - 0.9 μmol/kg。
