Worm K, Dragsholt C, Simonsen K, Kringsholm B
Institute of Forensic Medicine, Copenhagen O, Denmark.
Int J Legal Med. 1998;111(4):188-90. doi: 10.1007/s004140050147.
Concentrations of citalopram in medicolegal samples from 92 autopsies and 27 living persons are described. In autopsy cases in which citalopram alone was the cause of death, concentrations ranged from 2.0 to 6.2 mg/kg whole blood. In autopsy cases in which citalopram together with other substances was considered to be the cause of death, the concentrations of citalopram ranged from 0.6 to 5.2 mg/kg whole blood. In autopsy cases toxic concentrations ranged from 0.4 to 0.9 mg/kg whole blood and therapeutic concentrations from 0.03 to 0.6 mg/kg whole blood. In samples from living persons the concentrations of citalopram in whole blood were 0.02 to 0.3 mg/kg.
描述了来自92例尸检和27名活体的法医样本中舍曲林的浓度。在仅以舍曲林为死因的尸检病例中,全血中舍曲林浓度范围为2.0至6.2毫克/千克。在舍曲林与其他物质共同被认为是死因的尸检病例中,舍曲林浓度范围为0.6至5.2毫克/千克全血。在尸检病例中,中毒浓度范围为0.4至0.9毫克/千克全血,治疗浓度范围为0.03至0.6毫克/千克全血。在活体样本中,全血中舍曲林浓度为0.02至0.3毫克/千克。