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来自尸检和在世者样本中的西酞普兰浓度。

Citalopram concentrations in samples from autopsies and living persons.

作者信息

Worm K, Dragsholt C, Simonsen K, Kringsholm B

机构信息

Institute of Forensic Medicine, Copenhagen O, Denmark.

出版信息

Int J Legal Med. 1998;111(4):188-90. doi: 10.1007/s004140050147.

DOI:10.1007/s004140050147
PMID:9646161
Abstract

Concentrations of citalopram in medicolegal samples from 92 autopsies and 27 living persons are described. In autopsy cases in which citalopram alone was the cause of death, concentrations ranged from 2.0 to 6.2 mg/kg whole blood. In autopsy cases in which citalopram together with other substances was considered to be the cause of death, the concentrations of citalopram ranged from 0.6 to 5.2 mg/kg whole blood. In autopsy cases toxic concentrations ranged from 0.4 to 0.9 mg/kg whole blood and therapeutic concentrations from 0.03 to 0.6 mg/kg whole blood. In samples from living persons the concentrations of citalopram in whole blood were 0.02 to 0.3 mg/kg.

摘要

描述了来自92例尸检和27名活体的法医样本中舍曲林的浓度。在仅以舍曲林为死因的尸检病例中,全血中舍曲林浓度范围为2.0至6.2毫克/千克。在舍曲林与其他物质共同被认为是死因的尸检病例中,舍曲林浓度范围为0.6至5.2毫克/千克全血。在尸检病例中,中毒浓度范围为0.4至0.9毫克/千克全血,治疗浓度范围为0.03至0.6毫克/千克全血。在活体样本中,全血中舍曲林浓度为0.02至0.3毫克/千克。

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1
Citalopram concentrations in samples from autopsies and living persons.来自尸检和在世者样本中的西酞普兰浓度。
Int J Legal Med. 1998;111(4):188-90. doi: 10.1007/s004140050147.
2
[Citalopram in forensic samples. Citalopram concentrations in samples from legal autopsies and from living persons in connection with traffic accidents or cases of violence in Denmark 1989-1996].[法医样本中的西酞普兰。1989 - 1996年丹麦与交通事故或暴力案件相关的合法尸检样本及在世者样本中的西酞普兰浓度]
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Severe hypoglycaemia in citalopram overdose.西酞普兰过量导致的严重低血糖症。
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Fatal overdose with citalopram.西酞普兰致死性过量服用。
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Application of pharmacokinetic-pharmacodynamic modelling in management of QT abnormalities after citalopram overdose.药代动力学-药效学模型在西酞普兰过量后QT异常管理中的应用。
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Drug treatment of depression. Citalopram in overdose may result in serious morbidity and death.抑郁症的药物治疗。西酞普兰过量服用可能导致严重的发病和死亡。
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Citalopram is safe.西酞普兰是安全的。
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