Kim K, Mizunari T, Kobayashi S, Ishii S, Teramoto A
Department of Neurosurgery, Chiba Hokuso Hospital, Nippon Medical School, Tokyo.
No Shinkei Geka. 1999 Jul;27(7):645-50.
A case is presented of fenestration of the vertebral artery in a 36-year-old woman who had various neurological symptoms with Basedow's disease. We also review 7 cases from the literature. Our patient had had occipital neuralgia and numbness of the left side of the neck and left upper limb several weeks before admission. On admission she had hyperthyroidism. MRI, left vertebral angiography, and 3D-CT scans demonstrated a fenestrated vertebral artery compressing the upper cervical cord. The patient's symptoms gradually improved as her thyroid function was controlled. A possible explanation is that the fenestrated vertebral artery might have compressed the neural structures, resulting in her various symptoms. Occipital neuralgia was apparently caused by the fenestrated artery compressing the C1 and C2 sensory roots. A fenestrated vertebral artery is usually of no clinical significance. The reason for the late onset of symptoms in the present case is unknown, but it may have been due to hemodynamic stress caused by her hyperthyroidism. After her thyroid function was controlled, the hemodynamic stress presumably decreased and the symptoms resolved spontaneously.
本文报告一例36岁患有巴塞多氏病并伴有多种神经症状的女性患者椎动脉开窗畸形病例。我们还回顾了文献中的7个病例。我们的患者在入院前几周出现枕神经痛以及颈部左侧和左上肢麻木。入院时她患有甲状腺功能亢进症。MRI、左椎动脉血管造影和3D-CT扫描显示一条开窗畸形的椎动脉压迫上颈髓。随着甲状腺功能得到控制,患者的症状逐渐改善。一种可能的解释是,开窗畸形的椎动脉可能压迫了神经结构,导致她出现各种症状。枕神经痛显然是由开窗畸形的动脉压迫C1和C2感觉神经根引起的。椎动脉开窗畸形通常无临床意义。本例症状出现较晚的原因尚不清楚,但可能是由于甲状腺功能亢进症引起的血流动力学压力所致。在她的甲状腺功能得到控制后,血流动力学压力可能降低,症状自行缓解。