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1月龄时仰卧睡眠婴儿的短期发病率和婴儿死亡率——随访报告

Short-term morbidity and infant mortality among infants who slept supine at 1 month of age--a follow-up report.

作者信息

Dwyer T, Ponsonby A L, Couper D, Cochrane J

机构信息

Menzies Centre for Population Health Research, University of Tasmania, Australia.

出版信息

Paediatr Perinat Epidemiol. 1999 Jul;13(3):302-15. doi: 10.1046/j.1365-3016.1999.00194.x.

Abstract

Following evidence that prone sleeping is causally related to sudden infant death syndrome (SIDS), intervention campaigns to avoid prone sleeping in many countries have led to a large reduction in SIDS and total infant mortality. The supine position has been recommended for healthy infants in several countries. The objective of this report was to determine how usual sleep position at 1 month relates to morbidity indicators at 1 month and 12 weeks and to SIDS and postneonatal mortality using a prospective population-based live birth cohort in Tasmania, Australia. Eligible infants were the one-fifth of Tasmanian live births at higher risk of SIDS using a perinatal score. From 1 January 1988 to 31 December 1995, 9826 (89% of eligible) infants participated in the home interview. Fifty-three eligible infants died of SIDS, 51 (96%) with hospital interview data and 35 (81% of those eligible for home visit) with home visit data. The main outcome measures were SIDS, postneonatal mortality and parentally reported infant morbidity. The postneonatal mortality rates (cases per 1000 live births) by usual sleep position at 1 month of age were supine 1.60 [95% CI 0.04, 8.87], side 2.87 [1.79, 4.35], prone 10.27 [5.62, 17.18] and other (including no usual position) 6.37 [0.16, 34.98]. None of the study infants who slept supine died of SIDS at a later time. Of 25 morbidity indicators studied, only noisy breathing was increased for supine compared with side-sleeping babies. In this study, there was no evidence to suggest that supine sleeping at 1 month of age was associated with an increase in important short-term morbidity or postneonatal mortality. These findings provide further support for the recent recommendations of the American Academy of Pediatrics that healthy infants should preferably sleep in the supine position.

摘要

有证据表明俯卧睡眠与婴儿猝死综合征(SIDS)存在因果关系,许多国家开展了避免俯卧睡眠的干预活动,这使得SIDS和婴儿总死亡率大幅下降。几个国家已建议健康婴儿采用仰卧位。本报告的目的是利用澳大利亚塔斯马尼亚州一个基于人群的前瞻性出生队列,确定1个月时的常见睡眠姿势与1个月和12周时的发病指标以及SIDS和新生儿后期死亡率之间的关系。符合条件的婴儿是使用围产期评分在塔斯马尼亚州出生且患SIDS风险较高的五分之一活产婴儿。1988年1月1日至1995年12月31日,9826名(89%符合条件)婴儿参与了家庭访谈。53名符合条件的婴儿死于SIDS,其中51名(96%)有医院访谈数据,35名(81%符合家庭访视条件)有家庭访视数据。主要结局指标为SIDS、新生儿后期死亡率和家长报告的婴儿发病率。1个月大时常见睡眠姿势的新生儿后期死亡率(每1000例活产病例数)分别为:仰卧位1.60[95%可信区间0.04,8.87],侧卧位2.87[1.79,4.35],俯卧位10.27[5.62,17.18],其他(包括无常见姿势)6.37[0.16,34.98]。没有仰卧睡眠的研究婴儿后来死于SIDS。在研究的25项发病指标中,与侧睡婴儿相比,仰卧婴儿仅呼吸嘈杂情况有所增加。在本研究中,没有证据表明婴儿1个月大时仰卧睡眠会增加重要的短期发病率或新生儿后期死亡率。这些发现为美国儿科学会最近建议健康婴儿最好采用仰卧位睡眠提供了进一步支持。

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