Gilabert J, Aznar J, Parrilla J J, Regañon E, Vila V, Estelles A
Thromb Haemost. 1978 Oct 31;40(2):387-96.
Various tests of hemostasis were carried out during pregancy, labour and the puerperium in a group of 259 women. Determinations were carried out in the 1st, 2nd and 3rd trimesters, in the period of dilatation, the expulsion period, the period of expulsion of the placenta and the immediate postpartum period of labour and on each of the first 5 days of the puerperium. It was confirmed that during pregnancy there is an elevation of the fibrinogen degradation products (FDP) levels with a proportional increase in the numbers of positive protamine sulfate and ethanol tests. The proportion of positive protamine sulfate and ethanol tests reaches a maximum in the expulsion of the placenta coinciding with the presence of soluble complexes heavier than fibrinogen as detected by polyacrylamide gel electrophoresis and by column chromatography. All this indicates that there is a transitory intravascular coagulation produced during labour reaching its maximum at the time of birth and tending to become normalized in the first few days of the puerperium.
对259名女性在孕期、分娩期及产褥期进行了各种止血测试。在妊娠的第1、2、3个 trimester（孕期阶段）、宫颈扩张期、胎儿娩出期、胎盘娩出期、分娩后即刻以及产褥期的头5天分别进行了测定。证实孕期纤维蛋白原降解产物（FDP）水平升高，硫酸鱼精蛋白和乙醇试验阳性数相应增加。硫酸鱼精蛋白和乙醇试验阳性比例在胎盘娩出时达到最高，此时通过聚丙烯酰胺凝胶电泳和柱色谱法检测到存在比纤维蛋白原更重的可溶性复合物。所有这些表明分娩期间会产生短暂的血管内凝血，在出生时达到高峰，并在产褥期的头几天趋于恢复正常。
