Cover B, Gutteridge W E, Wharton F P
Trans R Soc Trop Med Hyg. 1978;72(6):596-601. doi: 10.1016/0035-9203(78)90009-3.
The course of infection of both blood and tissues by the Sonya strain of Trypanosoma cruzi in gamma-irradiated rats has been investigated. The blood infection was dimorphic; slender and broad forms were present throughout, though broad forms predominated at high parasitaemias. Both total blood parasitaemia and numbers of slender forms increased progressively in a series of waves with a periodicity of about four days. The rate of increase in the numbers of intracellular parasites corresponded with this, suggesting that the intracellular development cycle is also about four days. Tissue infection appeared to originate at the site of subcutaneous infection but subsequently occurred in the heart, and then later in the muscle of the hind limbs and alimentary tract.
对克氏锥虫索尼娅株在γ射线照射大鼠体内血液和组织的感染过程进行了研究。血液感染呈双态性；整个过程中均存在细长型和宽阔型，不过在高寄生虫血症时宽阔型占主导。总血液寄生虫血症和细长型的数量呈一系列约四天周期的波状逐渐增加。细胞内寄生虫数量的增加速率与此相符，表明细胞内发育周期也约为四天。组织感染似乎始于皮下感染部位，但随后出现在心脏，之后又出现在后肢肌肉和消化道。
