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[脊椎动物宿主体内克氏锥虫的多态性]

[Polymorphism of Trypanosoma cruzi in the blood of a vertebrate host].

作者信息

Kallinikova V D, Donchenko T G

出版信息

Parazitologiia. 1985 Nov-Dec;19(6):424-33.

PMID:3937117
Abstract

Tetramorphism of trypomastigote forms has been discovered in the blood stream of mice infected with Trypanosoma cruzi, that is C slender, C middle, S slender, S middle and forms intermediate between C and S. Regular changes of forms have been observed in the course of the infection. In the middle of the process, at the moment of maximum destruction of parasites affected by immunosystems of the host, C-forms prevailing on the whole substantially give place to S-forms, slender variants being replaced by middle ones within each of them. Polymorphism in the bloodstream of the vertebrate host is the general property of all trypanosomes, with their common biological value: immunological adaptation to parasitism in the blood and preadaptation to the continuation of the life cycle in the invertebrate host.

摘要

在感染克氏锥虫的小鼠血液中发现了锥鞭毛体形式的四形性,即C细长型、C中间型、S细长型、S中间型以及C和S之间的中间形式。在感染过程中观察到了形式的规律性变化。在过程中期,即在宿主免疫系统对寄生虫破坏达到最大程度时,总体上占主导的C型基本上被S型取代,在每种类型中细长变体被中间变体所取代。脊椎动物宿主体内血液中的多态性是所有锥虫的普遍特性,具有共同的生物学意义:对在血液中寄生的免疫适应以及对在无脊椎动物宿主体内延续生命周期的预适应。

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