由NH(4)CN聚合反应生成鸟嘌呤。

Production of guanine from NH(4)CN polymerizations.

作者信息

Levy M, Miller S L, Oró J

机构信息

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0506, USA.

出版信息

J Mol Evol. 1999 Aug;49(2):165-8. doi: 10.1007/pl00006539.

DOI:10.1007/pl00006539

PMID:10441668

Abstract

The synthesis of adenine from the polymerization of concentrated ammonium cyanide solutions is well known. We show here that guanine is also produced by this reaction but at yields ranging from 10 to 40 times less than that of adenine. This synthesis is effective at both +80 and -20 degrees C. Since high concentrations of NH(4)CN are obtainable only by freezing, this prebiotic synthesis would be applicable to frozen regions of the primitive Earth, the Jovian satellite Europa and other icy satellites, and the parent body of the Murchison meteorite.

摘要

由浓氰化铵溶液聚合合成腺嘌呤是众所周知的。我们在此表明，鸟嘌呤也可通过该反应产生，但产量比腺嘌呤低10至40倍。该合成在80摄氏度和零下20摄氏度时均有效。由于只有通过冷冻才能获得高浓度的NH₄CN，这种前生物合成将适用于原始地球的冰冻区域、木星卫星木卫二和其他冰卫星以及默奇森陨石的母体。